U
Sr. Research Associate, Voit Lab
Salary undisclosed
Apply on
Original
Simplified
WHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report , we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career!
JOB SUMMARY
The laboratory of Dr. Richard Voit, in the Department of Pediatrics, Division of Pediatric Hematology and Oncology, at UT Southwestern seeks to recruit a highly motivated individual who is interested in performing research at the intersection of hematopoiesis, cancer biology, and gene therapy to join our team as a senior research associate and laboratory manager. We are studying how perturbations in the transcriptional regulation of hematopoietic stem cells (HSCs) leads to bone marrow failure and acute myeloid leukemia (AML). We are also developing gene therapy approaches for inherited bone marrow failure syndromes. We use CRISPR perturbation, lentiviral transduction, and targeted protein degradation in primary human HSCs, bone marrow samples from patients with bone marrow failure and AML, and relevant human cell models to elucidate mechanisms of hematopoietic cell fate decisions and uncover targetable vulnerabilities in leukemia.
The selected candidate will work on experimental research projects directly with the laboratory principal investigator and other lab personnel (50% effort) and will spend the remaining 50% effort assisting with organization, management, and maintenance of the laboratory. A highly motivated and productive individual may get the opportunity to lead an independent research project within the laboratory.
A PhD is preferred, preferably with formal study in molecular biology, genetics, biochemistry, chemistry, or computational biology. The candidate must be a responsible individual with strong communication, organizational, and interpersonal skills. Experience with mice or culture of blood cells is not required, but enthusiasm for learning such approaches is essential. Individuals will have an opportunity to learn and use techniques in CRISPR editing, flow cytometry, next-generation sequencing, xenotransplantation, and quantitative PCR. Additionally, experience with computational biology could be helpful.
BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
EXPERIENCE AND EDUCATION
Required
JOB DUTIES
SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
EEO Statement
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report , we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career!
JOB SUMMARY
The laboratory of Dr. Richard Voit, in the Department of Pediatrics, Division of Pediatric Hematology and Oncology, at UT Southwestern seeks to recruit a highly motivated individual who is interested in performing research at the intersection of hematopoiesis, cancer biology, and gene therapy to join our team as a senior research associate and laboratory manager. We are studying how perturbations in the transcriptional regulation of hematopoietic stem cells (HSCs) leads to bone marrow failure and acute myeloid leukemia (AML). We are also developing gene therapy approaches for inherited bone marrow failure syndromes. We use CRISPR perturbation, lentiviral transduction, and targeted protein degradation in primary human HSCs, bone marrow samples from patients with bone marrow failure and AML, and relevant human cell models to elucidate mechanisms of hematopoietic cell fate decisions and uncover targetable vulnerabilities in leukemia.
The selected candidate will work on experimental research projects directly with the laboratory principal investigator and other lab personnel (50% effort) and will spend the remaining 50% effort assisting with organization, management, and maintenance of the laboratory. A highly motivated and productive individual may get the opportunity to lead an independent research project within the laboratory.
A PhD is preferred, preferably with formal study in molecular biology, genetics, biochemistry, chemistry, or computational biology. The candidate must be a responsible individual with strong communication, organizational, and interpersonal skills. Experience with mice or culture of blood cells is not required, but enthusiasm for learning such approaches is essential. Individuals will have an opportunity to learn and use techniques in CRISPR editing, flow cytometry, next-generation sequencing, xenotransplantation, and quantitative PCR. Additionally, experience with computational biology could be helpful.
BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare-no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
- Learn more about these and other UTSW employee benefits!
EXPERIENCE AND EDUCATION
Required
- Education
PhD With major coursework in field of assignment and no experience or
Master's Degree With major coursework in field of assignment
Bachelor's Degree with major coursework in field of assignment
- Experience
No experience required with PhD or
5 years Of laboratory experience; including at least 2 years At level of Research Associate or equivalent with Master's Degree or
6 years Of laboratory experience; including at least 2 years At level of Research Associate or equivalent with Bachelor's Degree
JOB DUTIES
- Organizes laboratory to which assigned; determines work assignments of subordinates, advising them as to techniques, procedures, and equipment to be utilized in solution of work problems; reviews completed work for professional quality and attainment of desired results.
- Compiles and evaluates research data, and develops new or revised techniques and procedures based upon such data.
- Performs or supervises design, development, or adaptation of equipment or apparatus used in experiments or research to obtain desired results.
- Compiles and analyzes results of research assignments and submits to principal investigator.
- Instructs medical students, graduate students, residents, and other laboratory personnel of lower grade with respect to techniques, procedures, and equipment utilized in research or experiments.
- Confers with industrial, governmental, or other professional groups with respect to progress or results of research assignment.
- Assists principal investigator and other professional personnel in preparation of reports and papers for publication, usually exercising responsibility for writing of particular segment or phase of report or paper.
- Performs other duties as assigned.
SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
EEO Statement
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
Employers have access to artificial intelligence language tools (“AI”) that help generate and enhance job descriptions and AI may have been used to create this description. The position description has been reviewed for accuracy and Dice believes it to correctly reflect the job opportunity.
Report this job Similar Jobs
