Senior Research Associate, Analytical Development/Mass Spectrometry

Encoded Therapeutics is a clinical-stage genetic medicines company developing potentially disease-modifying therapies to improve the lives of people with severe CNS disorders. Our proprietary vector engineering approach combines novel regulatory elements and payloads with AAV vectors to unlock innovative solutions for debilitating, intractable CNS conditions. At the forefront is our flagship clinical program, ETX101 for Dravet syndrome, which targets the underlying cause of the disorder to enable highly selective upregulation of SCN1A for potentially long-lasting benefit. In parallel, we are advancing a pipeline of potentially best-in-class programs to address significant unmet needs across both monogenic and prevalent CNS conditions. For more information, please visit www.encoded.com.

Encoded is seeking a Senior Research Associate, Analytical Development/Mass Spectrometry. Tthis position is based at Encoded s corporate office in South San Francisco.

• Design and perform protein characterizations including intact MS, Peptide mapping and HCP analysis by proteomics
• Develop and optimize protein chemistry and biophysical characterization methods including HPLC (SEC, IEX, Affinity, RPLC) and CE
• Collaborate with cross-functional teams to support analytical development, process development and comparability studies.
• Operate under Good Documentation Practice for efficient data management and retrieval.
• Record experimental procedure and results accurately in laboratory notebooks
• Work on multiple projects to meet departmental and organization goals

Requirements

• MS/BS in a relevant area of specialization (analytical chemistry, biochemistry) and 3+/5+ years of industry experience.
• Experience in analytical method development, including HPLC (SEC, RPLC, IEX, Affinity) and LC-MS (intact MS, Peptide mapping and proteomics) is highly desirable.
• Experience in CE and ELISA is a plus.
• Highly motivated, flexible and independent, yet successful in a group setting.
• Strong technical skills along with key competencies including attention to detail, meticulous execution of protocol, excellent organizational and interpersonal capabilities.
• Personnel characteristics of integrity, teamwork and commitment to excellence to fit with Encoded core values for success.

The anticipated salary range is $92,000 - $113,800. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, education, etc. Encoded Therapeutics is a multi-state employer and this salary range may not reflect positions that work in other states.

A hired applicant may be eligible for an annual bonus as well as equity under the company s stock plan.

Benefits

• Comprehensive benefits package, including competitive employer premium contributions
• Meaningful stock option grants
• PTO, sick time and holiday pay
• Generous Parental Leave program
• Pre-tax medical and dependent care programs
• STD, LTD, Life and AD&D
• Professional development opportunities
• Team-building events
• Fully stocked kitchen
• Purple Tie dry cleaning service
• Fitness center

Encoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Encoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate. Encoded will not tolerate discrimination or harassment based on any of these characteristics. Encoded encourages applicants of all ages.

If you need assistance or an accommodation due to a disability, you may call us at +1 650-491-0272.