B
Senior Scientist: Assay Development & Screening , Biotherapeutics
Salary undisclosed
Apply on
Original
Simplified
Description
Boehringer Ingelheim is currently seeking a talented and innovative assay scientist to join the Biotherapeutics Department located at our Ridgefield, CT facility. As a Senior Scientist, you will be an integral member of the Antibody Generation Group and you will participate in efforts to develop and integrate cell-based functional assays including, but not limited to, reporter gene, downstream signaling, internalization, proliferation, & apoptosis to support our drug discovery efforts for biologics. This individual will be expected to make contributions to the generation of first-in-class therapeutics based on an understanding of the NBE process and target biology.
As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.
Duties & Responsibilities
This is a lab-based position with at least 50% of time spent in screening, profiling, and characterization of biotherapeutics; the ideal candidate will aspire to and grow into more managerial responsibilities.
Responsible for design, development and implementation of robust and reliable biochemical and cell-based mechanistic assays using a range of assay techniques and platforms.
Guiding assay development, screening and characterization effort within the Screening Hub, oversees experiment design and data generation, and problem solving; Directs and oversees experimental data analysis and interpretation with the ability to advise and guide decisions of project teams.
Leads the identification and incorporation of new technologies or best practices to enhance antibody generation and discovery process. Proactively identifies and proposes external collaborations and assumes departmental responsibility for a portfolio project.
Communicates effectively orally and in writing in an inter-disciplinary environment; Discusses own work in the context of team and department goals in a concise and accurate manner; Keeps abreast of relevant literature and serves as resource in area of specialized expertise; Develops and maintains external visibility.
Complies with all applicable regulations; Ensures that work performed in area of responsibility is conducted in a safe and compliant manner; Maintains proper records in accordance with SOPs and policies.
Contributes to departmental administration; Demonstrates fiscal responsibility with respect to cost of experiments, technology, external collaborations, and travel.
Requirements
Ph.D. or equivalent in molecular/cellular biology, biochemistry, or related discipline with 2-5 years industrial or academic experience.
Desired Experience, Skills and Abilities:
Strong background and industrial experience in assay development techniques for all major target classes including GPCRs, Enzymes, transporters, ion channels, etc. Familiarity with high-density assay plate formats and automated liquid handling devices is highly desirable.
Expert and broad knowledge of assay development methodologies, including HTRF, LANCE/DELFIA, AlphaLisa, MSD, and BLI, and different detection technologies including FRET, luminescence (enzyme complementation), fluorescence, and absorbance. Hands-on experience with flow cytometry and high content screening is a plus.
Extensive experience performing assay data capture and analysis using software such as Genedata Biologics, Spotfire, and Prism. Outcomes-oriented and attentive to detail attributed to strong analytical skills.
Adaptability to frequent change and thrive in a dynamic and entrepreneurial environment.
Compensation Data
This position offers a base salary typically between $120,000 and $205,000. The position may be eligible for a role specific variable or performance-based bonus and or other compensation elements. For an overview of our benefits please click here.
Boehringer Ingelheim is currently seeking a talented and innovative assay scientist to join the Biotherapeutics Department located at our Ridgefield, CT facility. As a Senior Scientist, you will be an integral member of the Antibody Generation Group and you will participate in efforts to develop and integrate cell-based functional assays including, but not limited to, reporter gene, downstream signaling, internalization, proliferation, & apoptosis to support our drug discovery efforts for biologics. This individual will be expected to make contributions to the generation of first-in-class therapeutics based on an understanding of the NBE process and target biology.
As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.
Duties & Responsibilities
This is a lab-based position with at least 50% of time spent in screening, profiling, and characterization of biotherapeutics; the ideal candidate will aspire to and grow into more managerial responsibilities.
Responsible for design, development and implementation of robust and reliable biochemical and cell-based mechanistic assays using a range of assay techniques and platforms.
Guiding assay development, screening and characterization effort within the Screening Hub, oversees experiment design and data generation, and problem solving; Directs and oversees experimental data analysis and interpretation with the ability to advise and guide decisions of project teams.
Leads the identification and incorporation of new technologies or best practices to enhance antibody generation and discovery process. Proactively identifies and proposes external collaborations and assumes departmental responsibility for a portfolio project.
Communicates effectively orally and in writing in an inter-disciplinary environment; Discusses own work in the context of team and department goals in a concise and accurate manner; Keeps abreast of relevant literature and serves as resource in area of specialized expertise; Develops and maintains external visibility.
Complies with all applicable regulations; Ensures that work performed in area of responsibility is conducted in a safe and compliant manner; Maintains proper records in accordance with SOPs and policies.
Contributes to departmental administration; Demonstrates fiscal responsibility with respect to cost of experiments, technology, external collaborations, and travel.
Requirements
Ph.D. or equivalent in molecular/cellular biology, biochemistry, or related discipline with 2-5 years industrial or academic experience.
Desired Experience, Skills and Abilities:
Strong background and industrial experience in assay development techniques for all major target classes including GPCRs, Enzymes, transporters, ion channels, etc. Familiarity with high-density assay plate formats and automated liquid handling devices is highly desirable.
Expert and broad knowledge of assay development methodologies, including HTRF, LANCE/DELFIA, AlphaLisa, MSD, and BLI, and different detection technologies including FRET, luminescence (enzyme complementation), fluorescence, and absorbance. Hands-on experience with flow cytometry and high content screening is a plus.
Extensive experience performing assay data capture and analysis using software such as Genedata Biologics, Spotfire, and Prism. Outcomes-oriented and attentive to detail attributed to strong analytical skills.
Adaptability to frequent change and thrive in a dynamic and entrepreneurial environment.
Compensation Data
This position offers a base salary typically between $120,000 and $205,000. The position may be eligible for a role specific variable or performance-based bonus and or other compensation elements. For an overview of our benefits please click here.
Employers have access to artificial intelligence language tools (“AI”) that help generate and enhance job descriptions and AI may have been used to create this description. The position description has been reviewed for accuracy and Dice believes it to correctly reflect the job opportunity.
Report this job Similar Jobs
