Clinical PK Associate

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

This is a unique opportunity for a professional with non-compartmental PK analysis experience working in the development organization. Clinical PK Associate will be a key part of the Clinical Pharmacology function supporting clinical study execution teams. As a Clinical PK Associate, you will also be assisting Clinical Pharmacology and cross-functional clinical teams to ensure the successful execution of Clinical Pharmacology strategies.

Responsibilities

• Review pharmacokinetics concentration data & conduct non-compartmental PK analysis.
• Assist in summarizing PK data and generate TFLs to support Clin Pharm updates.
• Liaise with Clinical Pharmacology Project Leads to support reviews of the pharmacokinetics components of a clinical protocol, IB and other study associated documents.
• Facilitate clinical PK header reconciliation.
• Assist in collaborations with Clinical Pharmacology CROs to support PK analysis for clinical study reports and relevant sections of regulatory filing documents.
  
  

Required Experience, Skills, And Education

• MS in Analytical Chemistry, Pharmacokinetics, drug metabolism or a related scientific discipline with 3 years of relevant industry experience, or BS with over 5 years of relevant industry experience.
• Prior experience in non-compartmental PK analysis using Phoenix WinNonlin.
• Experience in supporting NCA in Phase 1, Phase 2 clinical trials.
• Excellent interpersonal, oral, and written communication skills.
• Thrives in a collaborative team setting and is driven by a desire to be innovative in a high energy, small company environment.
  
  

Preferred Skills

• Basic R programming.
• Experience in supervising BA CRO.
• Good understanding of regulatory guidelines for regulated bioanalysis.
• Good understanding of ADME related studies.
  
  

The base salary range for this full-time position is $ to $ for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].

LI-Hybrid

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity

This is a unique opportunity for a professional with non-compartmental PK analysis experience working in the development organization. Clinical PK Associate will be a key part of the Clinical Pharmacology function supporting clinical study execution teams. As a Clinical PK Associate, you will also be assisting Clinical Pharmacology and cross-functional clinical teams to ensure the successful execution of Clinical Pharmacology strategies.

Responsibilities

• Review pharmacokinetics concentration data & conduct non-compartmental PK analysis.
• Assist in summarizing PK data and generate TFLs to support Clin Pharm updates.
• Liaise with Clinical Pharmacology Project Leads to support reviews of the pharmacokinetics components of a clinical protocol, IB and other study associated documents.
• Facilitate clinical PK header reconciliation.
• Assist in collaborations with Clinical Pharmacology CROs to support PK analysis for clinical study reports and relevant sections of regulatory filing documents.
  
  

Required Experience, Skills, And Education

• MS in Analytical Chemistry, Pharmacokinetics, drug metabolism or a related scientific discipline with 3 years of relevant industry experience, or BS with over 5 years of relevant industry experience.
• Prior experience in non-compartmental PK analysis using Phoenix WinNonlin.
• Experience in supporting NCA in Phase 1, Phase 2 clinical trials.
• Excellent interpersonal, oral, and written communication skills.
• Thrives in a collaborative team setting and is driven by a desire to be innovative in a high energy, small company environment.
  
  

Preferred Skills

• Basic R programming.
• Experience in supervising BA CRO.
• Good understanding of regulatory guidelines for regulated bioanalysis.
• Good understanding of ADME related studies.
  
  

The base salary range for this full-time position is $ to $ for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact [email protected].

LI-Hybrid