Scientist

Responsibilities:

• The main goal of this group is to develop and execute assays that will predict the disposition of drug candidates and provide insights into the potential for drug-drug interactions by being a substrate or inhibitor of drug metabolizing transporters.
• Successful candidates should have a passion for generating high quality in vitro data for use by project teams across a range of therapeutic areas and must have independent bench level skills for working with a range of in vitro assay systems as well as the capacity to contribute to complex research projects.

Qualifications:

• Master’s degree in a relevant field (e.g. Biochemistry, Biology, Biotechnology, Molecular and Cell Biology, Pharmacology; Pharmaceutical Sciences) with 0-3+ years relevant experience
• Bachelor’s degree in a relevant field (see above) with 5+ years relevant experience

Required Experience and Skills:

• Cell culture, including routine maintenance using aseptic cell culture technique and ability to perform experiments per established protocols
• Track record of working collaboratively in a team environment delivering results for complex in-vitro biological systems
• Data analysis and interpretation using tools such as Excel, Graphpad PRISM, ability to document results
• Autonomy, attention to detail, critical thinking, growth mindset

Preferred Experience and Skills:

• Experience conducting in-vitro drug transporter or metabolism studies such as substrate phenotyping and inhibition assays in recombinant cell lines, vesicles and primary hepatocytes or comparable cell-based systems
• Experience with automation and/or developing complex liquid handling methodologies for in vitro experiments
• Basic understanding of quantitation using radiometric or LC/MS methods.

Responsibilities:

• The main goal of this group is to develop and execute assays that will predict the disposition of drug candidates and provide insights into the potential for drug-drug interactions by being a substrate or inhibitor of drug metabolizing transporters.
• Successful candidates should have a passion for generating high quality in vitro data for use by project teams across a range of therapeutic areas and must have independent bench level skills for working with a range of in vitro assay systems as well as the capacity to contribute to complex research projects.

Qualifications:

• Master’s degree in a relevant field (e.g. Biochemistry, Biology, Biotechnology, Molecular and Cell Biology, Pharmacology; Pharmaceutical Sciences) with 0-3+ years relevant experience
• Bachelor’s degree in a relevant field (see above) with 5+ years relevant experience

Required Experience and Skills:

• Cell culture, including routine maintenance using aseptic cell culture technique and ability to perform experiments per established protocols
• Track record of working collaboratively in a team environment delivering results for complex in-vitro biological systems
• Data analysis and interpretation using tools such as Excel, Graphpad PRISM, ability to document results
• Autonomy, attention to detail, critical thinking, growth mindset

Preferred Experience and Skills:

• Experience conducting in-vitro drug transporter or metabolism studies such as substrate phenotyping and inhibition assays in recombinant cell lines, vesicles and primary hepatocytes or comparable cell-based systems
• Experience with automation and/or developing complex liquid handling methodologies for in vitro experiments
• Basic understanding of quantitation using radiometric or LC/MS methods.