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Senior Scientist/Associate Director

Salary undisclosed

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Job Description

Job Description

Senior Scientist/Principal Scientist/Associate Director DMPK

Job Title: Senior Scientist/Principal Scientist/Associate Director DMPK
Location: Exton, Pennsylvania
Department: Drug Metabolism and Pharmacokinetics (DMPK)
Reports to: Assistant VP

Full Time

Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.

Job Description:

We are seeking an experienced and highly motivated Senior Scientist, Principal Scientist, or Associate Director to join our DMPK team. This position offers the opportunity to work in a dynamic environment that supports drug discovery and development programs.

Key Responsibilities:

  • Conduct in vitro and in vivo ADME studies using radiolabeled and non-radiolabeled compounds.
  • Perform sample analysis using a range of analytical instruments, including sample oxidizers, liquid scintillation counting (LSC), and LC/MS.
  • Manage labs to ensure proper instrument maintenance and documentation of equipment/instruments usage, calibration, and services.
  • Prepare study protocols, oversee study conduct, collect and summarize data, and write/review reports to meet study timelines.
  • Ensure all lab operations and record-keeping are of high quality and compliant with Frontage SOPs, DMPK guidelines, study protocol and applicable regulations.
  • Manage multiple tasks/projects simultaneously to meet internal/external deadlines, fostering collaboration within the DMPK team.
  • Provide training and mentorship to junior scientists in key areas of drug development.
  • Demonstrate expertise in leading cross-functional, matrix-based project teams, taking accountability and guiding them to successful outcomes.
  • Provide scientific leadership and direction to clients and development teams for ongoing and prospective programs.

Qualifications:

  • PhD in Biochemistry, Pharmacology, Chemistry, or a related field with 5-10+ years of relevant experience, or a Master s degree with 10-15+ years of experience in DMPK, ADME, or a related field.
  • Significant experience in leading ADME studies, particularly with radiolabeled compounds.
  • Proven leadership experience in managing teams and delivering on tight deadlines while maintaining high standards of data quality.
  • Excellent communication and leadership skills, with the ability to collaborate effectively across functions and levels.
  • Familiarity with GLP compliance and EPA rules/regulations is a plus.

Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

Employers have access to artificial intelligence language tools (“AI”) that help generate and enhance job descriptions and AI may have been used to create this description. The position description has been reviewed for accuracy and Dice believes it to correctly reflect the job opportunity.
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