Senior Scientist, CAR Screening and Lead Selection, Cell Therapy Platform & Discovery

Description

Johnson & Johnson is recruiting a Senior Scientist, CAR Screening and Lead Selection, Cell Therapy Platform & Discovery, based in Spring House, Pennsylvania.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

For more than 130 years, diversity, equity & inclusion has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges. We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued, and our people can reach their potential. At Johnson & Johnson, we all belong.

We are seeking a highly motivated and experienced Senior Scientist to join our Cell Therapy team. In this role, you will play a key part in advancing our cutting-edge cell therapy programs by driving the development, optimization, and execution of experiments to enhance the therapeutic potential of our CAR T cell products, in addition to collaborating with cross-functional teams to support discovery activities. The ideal candidate will have a strong background in immunology, or related fields, with demonstrated experience in cell therapy focused assay development and execution. This role is a unique opportunity to contribute to scientific advancements that have the potential to revolutionize healthcare. Come join us and become part of a fast-paced team working to achieve curative responses in patients with cancer by building best-in-class cell therapies.

Key Responsibilities:

• Design, develop, and execute T cell-based experiments
• Analyze data from in vitro studies, providing insights and recommendations to drive decision-making.
• Collaborate closely with cross-functional teams to ensure alignment with project goals.
• Contribute to the preparation of technical reports and data packages.
• Aid in the mentorship and training of junior scientists and research associates, fostering a collaborative and innovative environment.
• Stay current on the latest scientific and technological advancements in cell therapy and related fields, and incorporate new knowledge into ongoing projects.
• Present findings and updates to senior leadership, internal stakeholders, and external partners as required.
• Ensure compliance with all relevant safety and quality standards.
• Maintain accurate and detailed records of experimental procedures, data, and results in a well-organized lab notebook, ensuring compliance with company standards and regulatory requirements.
• Ensure that all experiments are properly documented, reproducible, and accessible to team members and collaborators.

Qualifications

• Ph.D. in Cell Biology, Immunology, Molecular Biology, or a related field with 4-6 years of relevant postdoctoral or industry experience; or a Master's degree with 6+ years of equivalent experience in a biopharmaceutical or biotechnology setting.
• Strong expertise in cell-based therapy research, including experience with CAR T or similar platforms is required.
• Hands-on experience with cell culture, viral transduction, cytotoxicity assays (Incucyte-based preferred) and flow cytometry is required.
• Solid understanding of immunology and tumor biology, with experience in preclinical models (in vitro and in vivo) is preferred.
• Proven ability to lead scientific projects and deliver high-quality results and recommendations in a fast-paced, collaborative environment.
• Experience in preparing and reviewing technical reports is preferred.
• Demonstrated ability to analyze complex biological data sets, synthesize results, and provide actionable insights to guide experimental decisions and project strategies is required.
• Excellent communication and presentation skills, with the ability to convey complex scientific information to diverse audiences is required.
• Strong problem-solving skills, attention to detail, and a proactive, innovative mindset.
• Prior experience with automation and high-throughput screening for cell-based assays is preferred.

Why Join Us?

• Be part of a transformative journey in developing life-saving therapies.
• Work in a collaborative, innovation-driven environment.
• Opportunities for growth and professional development.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit

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